How do you know what you know? Neil deGrasse Tyson and comedian Chuck Nice explore issues with quantum mechanics and objectivity, the history of physics, and how scientists ask questions on the edge of our understanding with philosopher of physics Elise Crull.

What does loneliness do to our brains? Neil deGrasse Tyson, Chuck Nice, and Gary O’Reilly explore how the loneliness epidemic impacts our minds, bodies, and even our lifespan with neuroscientist Ben Rein, author of Why Brains Need Friends: The Science of Social Connection.

How can we build a new Moon program while slashing science funding? Bill Nye takes the host’s chair alongside Chuck Nice to tackle one of the most urgent issues facing our future in space with Casey Dreier, Chief of Space Policy at The Planetary Society, who’s been tracking and analyzing NASA’s funding for years.

Would Godzilla be structurally sound or too big for its own weight? Neil deGrasse Tyson, with co-host Matt Kirshen and “Geek-in-Chief” Charles Liu, takes a look at the monsters that have terrified us and the scary speculative science behind them.

Is there anything real left on the internet? Neil deGrasse Tyson and co-hosts Chuck Nice and Gary O’Reilly explore deepfakes, scams, and cybercrime with the Director of Threat Research at Bitdefender, Bogdan Botezatu.

What is nothing? Could a dying back hole cause the Big Bang? Neil deGrasse Tyson and comic co-host Chuck Nice answer fan questions about a black hole’s dying gasp, lunar eclipses, and the meaning of nothing.

What happens when you fall into a black hole? Neil deGrasse Tyson and Chuck Nice give us the step-by-step on spaghettification, explain Schrodinger’s cat, and explore quantum tunnelling… Or do they?

Is social media rewiring childhood and fueling a mental health crisis? Neil deGrasse Tyson, Chuck Nice, and Gary O’Reilly explore the costs of growing up online and how to take back childhood with social psychologist Jonathan Haidt.

What will the future of space look like? Neil deGrasse Tyson and comic co-host Chuck Nice explore the engineering challenges and scientific questions shaping the next era of aerospace with aerospace engineer Jeff Thornburg.

Can we resolve the crisis in cosmology? Neil deGrasse Tyson and co-host Matt Kirshen take on Hubble Tension, the difference between the estimated ages of the universe, and how to solve it with legendary astronomer Wendy Freedman.

What happens to your brain when you use AI? Neil deGrasse Tyson, Chuck Nice, and Gary O’Reilly explore current research into how large language models affect our cognition, memory, and learning with Nataliya Kosmyna, research scientist at the MIT Media Lab. Is AI good for us?

Could LISA detect primordial black holes or gravitational waves from the Big Bang? Neil deGrasse Tyson and co-host Chuck Nice explore LISA and the future of gravitational wave astronomy with astrophysicist Kelly Holley-Bockelmann.
