Combating Disease with Jimmy Carter

Welcome to StarTalk, your place in the universe where science and pop culture collide. StarTalk begins right now. WTF I'm your host, Neil deGrasse Tyson. I'm director of the Hayden Planetarium right here. And I've got with me one of my favorite co-hosts, Chuck Nice. Hey, Neil. Hey, comedian. How are you, man? You're good, good. Look at that, almost a smattering of applause for me. A sitting ovation, yes, Chuck. So you're native of Philly, right? I am a Philly native, yeah. Philadelphia. Philadelphia, the city of Philly. And I saw that big place where Rocky ran up the steps. The Art Museum. Is that what that is? Yes, that's what that would be. No, it's where Rocky ran up the steps. And you'd be surprised how many people refer to it just as that. Even though they went through all the problem of recreating the Parthenon, people were like, yeah, it's the Rocky place. I'm told, isn't there like a statue of the man at the top? No longer. Oh, good. There was until they realized he's not a real person. It's your hometown, I don't wanna, you know. It is my hometown. That's the only thing I'm a little ashamed of is that we put a statue of a fictitious boxer. I mean, this is the home of Joe Frazier and we have a statue of Rocky. Something wrong with that. So guess who I got to interview for this episode? I am. You know, I wanna boast or anything. You know, I have to say that this is a boast-worthy guest. You know who I got. I got President Jimmy Carter. Fantastic, man. JC himself. Yeah, no, not the JC. He's AJC. Lot of people right now are just like, what are you saying? That would be a gap if I got it. We would get like every rating point there was. Without a doubt. Sunday, Sunday, Sunday. I'm sorry, I couldn't help you. So he came through town, because he's collaborating with us on an exhibit called Countdown to Zero. He's trying to eradicate certain eradicatable diseases. And I thought, I can't take on that topic alone, because I be an astrophysicist and you be a comedian. So we had to bring on some top guns from elsewhere in the institution. My friend and colleague, Mark Siddall. Mark, give it up for Mark Siddall. You specialize in blood-sucking parasitic leeches. You know, I like to think that I care about the things that most people don't. Mark, when I was a kid, I looked up and I said, I want to study the universe. Where did you look to decide that you want to study parasites? I'm just curious, what kind of childhood did you have? I looked in the ravine that was across the road from my house where we were collecting snakes and frogs, and I just got really enwrapped in local ecosystems. At what age? Oh, God, maybe five or six. Five? Ecosystems, local ecosystems at age five. Okay, so you get a frog, you get a snake, you put them in a- Snakes eat frogs. You put them in a container in your backyard. Worst dating service ever. It's an ecosystem that has a result. Snake eats frog. Yeah. I mean, it's a learning experience. I spent a lot of time canoeing and kayaking and hiking and you just get fascinated with the way things are connected and it wasn't until I was a graduate student that I got this idea that all those connections between animals and plants and things that things eat carry all of these other parasites along. So Jimmy Carter came through town to this institution to help us inaugurate the new exhibit Countdown to Zero, which is all about parasites, right? Yeah. And the eradication of parasites. So I was like knowing whether people like presidents and other sort of people of high station in life that are not otherwise scientists, I always want to know, is there science in them somewhere? Yes. Do they carry some kind of secret geek credentials that we don't otherwise know? Let's find out with President Jimmy Carter. In my freshman year in college, I was the laboratory assistant for the person who taught astronomy. So you had an early sort of cosmic baptism. Well, I did it, and then I was in the Navy, too, so I learned how to navigate just from the stars. Yeah, now everyone's just got their GPS. I tell them, in my day, we had to actually know. Well, we did. I was on a ship with my family Christmas and I asked the captain if he had a section on board, he said, yes, we have one. And it was in a glass case over there. It never had been out of open. Never been open, but we had- Well, it was a special break glass, if necessary. An apocalyptic earth, that's all you have. Well, time has changed. How would you say that your knowledge of math or science in college and high school, has that influenced your politics? What I mean is your ability to think about world problems? Well, I was an engineer and I was a nuclear physicist. I was sent in charge of building the second atomic submarine. So I studied advanced physics. And then, of course, when I went into politics, being an engineer, I planned things, I made sure... You think differently from other politicians. I think in a way you do. You think differently from a lawyer or a doctor, somebody like that. And so... And most of Congress are lawyers, right? So you're really different. We need more engineers, more farmers, yeah. That's our man. Yeah, very cool. So he, after he became president, he started the Carter Center, and which is devoted to sort of promoting sort of democracy and health and well-being around the world and monitoring elections. And he's sort of a trusted soul around the world, right? He comes in, it's not, oh, here comes America, it's here comes Jimmy Carter, right? And so, but another one of their goals is to stamp out stampoutable diseases, right? This is... Yeah, that's correct. I mean, the Carter Center has been trying to do a lot of things in the president's post-presidency, arguably among the most productive post-presidencies of any American president. I mean, the hashtag, if you will, is waging peace. Right. But also eradicating disease, and those go hand in hand. And you're a disease guy. Well, I... I'd like not to think that I'm the disease guy. Yeah, because that would be terrible at cocktail parties. But these are among my concerns. I will agree. Disease and parasites. Parasites in particular. Leeches. And your Twitter handle is? I am The Leech Guy. See what I'm saying, Chuck? Chuck, see? The Leech Guy. Was I lying here? No, that's... Yeah. Is this the man or not? Or what? You know, I didn't think the disease guy could get any worse, but... The Leech Guy. The Leech Guy came along, so... Why The Leech Guy, Mark? Is that your concentration? I mean, a lot of the work that we do here, my students and I can concern leeches. I mean, it doesn't suck that bad. Ha ha ha! Don't groan on that! He got me! I was not expecting that, man! I get it. That was good! But, you know, here's the thing, is that biodiversity is really important, and it's kind of easy to get people to be worried about pandas and koala bears and spotted owls. Cute things. But honestly, everything out there is really valuable in its own way, and that includes leeches themselves. Yeah. Really? Really. Well, you know, it's funny, it's because I, now maybe I'm just not remembering correctly, but I think I read an article where leeches are now once again being used because there are some true medical benefits to leech, using leeches. Yeah, which hospital is that? Not just the leeches. And maybe it's just my health plan. Perhaps I just need a better health plan. Just like, you know, hey, Chuck, this is all you can afford. Take these leeches. I don't know if I'm right, though. No, you are. You are. I mean, it's funny. There was a couple of guys in Slovenia, a couple of guys in Slovenia figured out that you could use leeches to remove excess blood after reattaching a finger or an earlobe or whatever. Circulation is bad. Otherwise. Restoring circulation, that's exactly right. Leeches are actually really useful for that. They're not useful for those... In the 1800s, it was for obesity and hysteria and gout, but that didn't really... Well, it got out of hand. Like, you know what I mean? They just put some leeches on it. Whatever it is. Got a sore throat. Put some leeches on it. So tell me about other kinds of parasites. Do they split into categories? Because I think of ones that have been in the news, like bed bugs and headlights and crabs and stuff. I mean, what? And we're not talking dungeness. We know that. These are not Maryland crabs. We don't need that much information about which of these in this list you agree with. Well, I'd very much like to come back to your problem with crabs in terms of the fact, you know, extinction of various parasites. But in general, we do kind of broadly classify different parasites, ecto parasites, like leeches and bed bugs and lice. Ecto would mean? On the outside. Endo parasites, tapeworms and nematodes and... Things that get inside you and eat you from the inside out. And then there's also... I'm sorry to hijack right now. But now you just made me think of... Chuck, crabs just got him going here. Yeah. You know, that's what... He's a friend. No, it's really got her going. She left because of that. He's got a friend. He's got a friend. Okay, go on. So you said, you know, in terms of endo, how about a tick, which starts on the outside but burrows inside of you? Is that still considered like an... Ticks don't burrow. Oh, really? True. I thought that they did. Yeah, well, I mean, there's a... I mean, that's a common perception that people have. Sure, yeah. There are some of these insects that do burrow. There's actually a flea that burrows into your toe, the chigo flea, lays eggs along the way, and it's terrible. The vertebrates, like us, we're just the cans that the interesting things come in. So we're vessels for other animals to do their thing. Very much so. So Jimmy Carter has taken on the mission to eradicate one of the creepiest parasites on Earth, a worm that can grow more than two feet long before it slowly emerges from your skin. That's next when StarTalk returns. We're back on StarTalk from the Hall of the Universe. I got with me my co-host, Chuck Nice, tweeting at ChuckNiceComic. That's correct, sir. You got it. I had my friend and colleague, Mark Siddall, professor of genomics at the Sackler Institute, an entirely enclosed entity within the American Museum of Natural History. So Jimmy Carter came through town to this institution to help us inaugurate the new exhibit Countdown to Zero, which is all about parasites, right? Yeah. And the eradication of parasites, a major mission statement of the Carter Center, something he founded right after his presidency. Yeah, right after his presidency, the President Carter and Mrs. Carter put together the Carter Center. It's about waging peace. It's about- Waging peace, nice phrase. Nice, I like that. Wish it were mine, it's theirs. The Habitat for Humanity, and a really central part of that is actually trying to eradicate neglected tropical diseases, and they've done a lot on that. So of all of his portfolio of the Carter Center, the one that is manifest here is in the eradication of diseases. The eradication of disease. And you're advising on it, you're chief curator. I'm the curator of the exhibit, yeah. Chief curator of the exhibit, and one of their targets is diseases in general, but in particular, they were announcing progress on the Guinea worm. Guinea worm. What is the Guinea worm? Guinea worm is a, what we call a round worm parasite. It's actually not round, it's very, very long. It's about three feet long. Well round compared with like flat worms? Well, round if you cut it up in little pieces and you look at it on the end, but really. I'm telling you, what are we, we'd be round humans. We'd be round. My midsection would be round if you cut. Round primates. It's actually been with humanity for several thousands of years. We know that because we have a mummy that's in Birmingham, England, that's got a Guinea worm in it that we can see with CT scanning. We know from the Bible, in fact, the fiery serpents that were referenced in the Bible are clearly about Guinea worm. This is a parasite that's afflicted humans for so long, and it's actually the only parasite of humans that must cause pain in order to complete the life cycle. Oh, so it's like my mom. So why single out the Guinea worm compared to anything else? This is one of those conditions where only humans are infected and there is a way to intercede in the life cycle to eradicate the disease. When those two things come together and you can deliver the services, you could actually come up with a campaign to eradicate a disease. So it's because the last person to have Guinea worm will be the last person to have Guinea worm. Absolutely. Because you can't catch it from another animal. That is correct. So that makes it an affliction within reach. It's part of the human niche. If we went extinct, so would Guinea worm. Absolutely. They need us. Absolutely. But we do not need them. Not that Guinea worm. So is there something else called a Guinea worm disease relative to Guinea worms? Right. So we try to separate the name of the organism from the condition. And a good example is malaria. Plasmodium falciparum, Plasmodium malariae. These are the organisms that cause malaria. Malaria is the name of the disease. Guinea worm disease is the affliction of having the Guinea worm within you. Correct. So these are huge undertakings to do this. They are. Going into places that are otherwise not, transportation is not good, communication isn't good, culture gets in the way. So I had to ask Jimmy Carter, how do these huge undertakings manifest in their efforts? Right. To do just that. Let's check it out. Sure. We found Guinea worm, for instance, in 20 countries, three in Asia and the rest of them in Sub-Saharan Africa, 23,600 villages. And we've been to every village, either we or the people we train. And we have just been able to give them the information of what causes the disease and what they can do to prevent it, and they have done the work, and so we give them credit for it, which always encourages success. It seems to me that's the only way you can be successful, is to get people to... To do it themselves. And to give them credit. Oh, of course. Yes, yes. So in a way, the Carter Center is not just your group of people at the center, it is the influence that it propagates. Exactly. And when we go into a country, we generally send one superb scientist who knows all about the disease and what causes it. And we teach step by step people who live in the country. So say in southern Sudan now, where we have the most cases of guinea worm... The most cases that remain. That remain, yes. And we had more cases in Nigeria, which has no cases now. But anyway, in South Sudan, we have about 120 people on our payroll who monitor the whole country. But we have about 8,000 to 12,000 volunteers, mostly women, who monitor every village. And as soon as a case of guinea worm develops, they immediately identify that person, keep them out of spreading the disease. Out of the water supply, basically. So he's in it. He's working it. And so, Mark, just before that clip, you talked about the guinea worm requiring that we be in pain. Yeah. What does that mean? When someone gets infected, let's say, in year one by drinking water that has... It's infected with the guinea worm. Infected with the guinea worm. Comes from drinking water that's got guinea worm in another host, a water flea. It takes a year, a whole year, for that worm to grow up to three feet long, let's say in a leg. The only way that the worm, the mother worm, is going to get to complete the life cycle is if she gets to water. You got to get out of the body and get back to the water and then lay to age. So the way she does that is she inflicts excruciating pain. So these are girl worms, not boy worms. The boys are dead by this point. Always the case. They've done their deed, they're no longer relevant, they're gone. So she'll inflict an incredibly excruciating, blistering burn in an extremity, usually a leg. That causes the afflicted person to go to water to get the soothing effect of water. And then she bursts her head out through the blister, dumps all of her young into the water and completes the life cycle. She must... That is diabolical. It is diabolical. These are dragons. Oh my God. That's the Alien movie. That is the alien, the little snake man pops out your chest and that's insane. And it's real and it's tragic. So what are the logistics of eradication? How do you combat this? Especially given that one year delay. Oh my gosh. How do you even get a cause and effect going there? Well, that's actually really cool that you asked about that because education is absolutely key. Getting people to understand that something that will come out of your leg in year two is a result of an action in year one is really difficult to do in a place where you don't have education, people don't read, people don't write, you don't have Twitter or what have you. There are other elements involved too. And I think the most critical thing has to do with empowering people on the ground. And I think this was actually learned from a smallpox campaign that happened back in the 70s. So, this is why you need somebody with the political influence and respect that Jimmy Carter gets. Absolutely, and in fact, President Carter has been able to... I mean, he's really interested in getting local communities acting, but he's managed to get leaders of adjacent countries to compete against each other. He used to call up the head of the country. Totally. You can't do that, but he can do that. I wouldn't even try. Well, I might try, but I don't know how far I'm going to get with that. Well, let's find out what steps he's taken in the Carter Center to deal with all of these cultural, political challenges. Well, the first step in the whole process is for me to go to the country, meet with the president and the minister of health and the minister of finance. So you get to do that as a former president? I love the way you say that. I'll just meet with the president. I could just do that. Well, I don't have to probably meet him at King's and that sort of thing. I'm just saying that's great. But we sign a minimum random of understanding, kind of like a contract or covenant, and they do certain things, we do certain things. And then we go in with our full support and permission and start going from one village to another. We don't send in money to the countries. We don't send in medicine to the countries. We don't send in filter cloths to the country. We make sure that our people deliver them directly to the village that is suffering from it. So the distribution channels you oversee, it's not just dropped off, it's not a drop off point. We're completely in charge of all the distribution channels. The filter cloths prevent, I guess, the larvae from coming through so you can drink a clean cup of water. You pour the water with the guinea worms in it through a very fine filter cloth, then you can drink the water that emerges. And how about in times of war? How do you get in? That's a very difficult time. That's been our biggest hole up in South Sudan, which has been at war now off and on for 25 years. We try to promote peace. We negotiate peace agreements and hold elections as well. But when a conflict breaks out in a region, quite often they'll steal our motorcycles, they'll steal our delivery trucks. Resources. Yeah, and they steal anything that's valuable, as well as attacking sometimes our own people who are there to help them do away with the disease. Another thing is that some of the countries have no way to keep their interests up. They get overconfident when we drop them down from, say, 200,000 cases to 2,500 cases. Then they get overconfident, and we can't get the president and the minister of health to cooperate. And they don't understand you've got to take it to zero. You've got to take it to zero, otherwise we'll come back. So, Mark, these challenges, he's talking about war. In your work, you've got to go around the world to find the parasite you so love. Do you ever have issues with war and politics? Yeah, twice. Once in Madagascar during a contested election, and in fact, when I was with the Carter Center in South Sudan, there was some conflict going on very nearby that really gets in the way of infrastructure and delivering services. But you can't do anything about it because you're not President Carter, if you're there alone. You know, I... You're a charming guy, but there's a limit, I think, right? Well, you're a generous man, but... But we need something for Chuck here. Chuck, you're a beautiful man. Well, you know, I'll take that. Yeah, I think even the people who are working on the ground, they don't see it as their job to try to fix those problems, although they do... They're very aware of how that gets in the way of getting the job done. But there are dangers of complacency, because... And it could be passive or active complacency. Sure. Passive would be, look, I got these other things on my plate, I can't worry about that now. Active would be, I choose to not worry about this because I don't think it's a problem. Well, I mean, fundamentally, it's whether or not you care about other people. Right. And this is the way that these disease eradication, whether it's guinea worm or smallpox or polio, it's so centered on a community caring about the whole community, an infection and what happens to your neighbor. I honestly think that what's going on with this measles epidemic is people failing to care about their community. You know why? Because they don't realize what their children are. And that is disease bags. I have three, so I'm not just saying this to say it. I have three of my own. All of them are designed to come here and accept and breed disease so that they can be stronger and in the process kill the rest of us. So, you know, that's what it is. It's Chuck's theory of biology. Chuck's not wrong. And that's the deal. They're in bed for two days, and then I'm in bed for a week and a half. I'm like, what did you... So, their immune system is getting practice. Right, while they're killing me because they're creating super diseases to pass along to me. So, when it comes to measles for an effective immunization regime, about 95% of a community has to be immune to it. Then the other 5%, they could not be vaccinated. That'd be fine. But let's move that on. That 5% are so scattered from one another, they're not going to spread it. Is that a matter of point of contact? It's all about contact. So, when you take something as infectious and insidious as Ebola, 95% is not enough. You would have to have a much higher level. You've got to go to zero. And it's really about a community caring about each other. But you have to somehow convince people that they need to do this. You need somebody with a diplomatic finesse. Absolutely. To pull that off. Yes. And of course, Jimmy Carter is known as a master of diplomacy. We'll find out how he used those same skills to take down the guinea worm. Coming up on StarTalk. So, we're talking about my interview with Jimmy Carter and his efforts to eradicate the guinea worm. Something of your specialty, Mark. You think about these kinds of things all the time. Every day. Which creeps me out, I just want you to know. Okay, just, just. That's fine. Okay, it doesn't creep you out. No. So the guinea worm, it's not called the American worm, it's not called the Russian worm. No. It's not called the Cuba worm. No. It's called the Guinea worm. But nobody wants a disease named after the country. That's certainly true. And President Carter knew this. He knew this. He did indeed. And he used this to his diplomatic advantage. Let's check it out. We had a very difficult problem in Ghana, which started out with 126,000 cases, and it got down to about 35 or 40, and it stayed there for about 10 years. So I finally went to the president three times and told him that we were gonna change the name of the other Guinea worm to Ghana worm. Right, because it's named after where it was first discovered, I guess, or diagnosed. And we raised a lot of political pressure on him, and he finally got the word, and he became interested, and now we have zero cases in Ghana. Clever, peaceful threat. I gotta remember that. Sometimes I got kind of angry with him, but it works. Nice. The man was just throwing it down. Yo, that is, I mean, that is a great little ploy. You know, Carter pulled off some more, he had some more tricks in his bag. You know, he wants peace. What's the hashtag? Waging peace. Waging peace, and he actually used the guinea worm to achieve peace in one incident. Absolutely. Let's find out how he did it. They had a war going on that was fought in dry seasons and wet seasons. A dry season was when Sudan, with tanks and so forth, could travel easily. The wet season was when the rivers flooded and the southern Sudanese could prevail. So I went there and negotiated for quite a while with the south and north, and finally they agreed on a ceasefire just so that we could do away with guinea worm, both in the north and south. And they still call it the guinea worm ceasefire. But they quit fighting for more than six months. That reminds me of, you know, you read about, it was in the First World War, there was the Christmas ceasefire or the Easter ceasefire, and it's a glimmer of hope that there's some humanitarian dimension. And it shows that if you give people a chance in a very poverty-stricken country to correct their own problems, they do it superbly. Is it possible that he could give Congress Guinea worms? Because that would be awesome. So, Mark, what is the relationship between disease and war? There's a very strong correlation. Probably the best example is if you go to the CDC website or the WHO... Center for Disease Control? Center for Disease Control website or the World Health Organization website, and you look at the distribution of polio right now, there's fewer than 500 new cases of polio a year, but they're in Waziristan, they're in Syria, they're in southern Somalia, and they're in northern Nigeria. These are places of conflict. And in fact, when I was with the Carter Center in South Sudan, there were some conflict going on very nearby that really gets in the way of infrastructure. And what goes on in a war-torn area is an inability to provide services and an inability to track cases and find out where they are. Both of those. At the front end and the back end, you lose the connection to health care, and it's devastating. So clearly, there are all kinds of challenges on this war on germs and parasites. And we'll find out how culture has played a role in the history of these diseases when we come back to StarTalk. We're back, StarTalk, Hall of the Universe. Chuck. Hey. Mark. Yes. You're helping us out here. We're trying to get rid of the guinea worm via our exhibits here and the Carter Center and... And I am actually gonna count my appearance on this show as my contribution to the eradication of the guinea worm. Thank you, Chuck. Put that on your resume, Chuck. When it happens, and I want to, Chuck Nice, comedian and eradicated guinea worm. Guinea worm. So, are we there? We're close, 126 cases left on the planet, down from three and a half million in 1986 because of the effort of the Carter Center. This is awesome. And you're working with them. I've been working with them in the field and principally been working with them on this exhibit that we've got here at the American Museum of Natural History. And that's a terrific thing because it's about celebrating this success as it's happening. In real time. In real time. All right, so it seems to me that they may occasionally be forces operating against success. We talked about war. We talked about education. Anything else? Sure, in South Sudan, in Mogos, in the containment center that we were in, there was a young man who came in who had a guinea worm and the local physician with traditional healing methods said they must have got it because one leg was in the spirit world and one leg was in the natural world. Of course, this isn't really how things go on, but in a community. Thanks for telling us. I don't know what to believe anymore. It reminds you what show you're on and what network this is appearing on. Well, and you know, and it's- Thanks for that assurance that his guinea worm affected leg was not in the spirit world. It's straightforward enough for people who like the three of us to say, well, clearly that's not the case. He got it from some water he drank the year before, but the connection's not that obvious to people who aren't that educated. The time delay prevents that. Time delay is huge. But I ask the president, President Carter, what challenges he's faced in this? Sure. Let's find out. Let's find out where he takes us. The guinea worm exists when you have a rain pond near a village, and that's the only source of water. So the people living in the village know that their ancestors lived and their parents lived and they lived because that pond existed. And sometimes they look on the pond is sacred. And for us to go in and tell them that the pond, which you consider to be sacred, is causing this disease, they have an adverse reaction to it. And also the medicine man and other things, quite often they make their living wrapping the guinea worm as it emerges from the body. It takes about 30 days. They wrap it around a stick, about as big as a pencil, and you can make it come out in 20 days. That's the only way they had to treat it for thousands and thousands of years. So when we tell them what caused it, what to do about it, sometimes we have an adverse reaction. As a matter of fact, that's really the symbol for Dr. de Caduceus. That's what I was wondering, because there's a serpent wrapped around a... It's not a serpent, it's a guinea worm. It's a guinea worm, okay. Yeah, that's fine too. And it's in the Old Testament, too. The fiery serpent that attacked the Israelites coming out of Egypt was a guinea worm. By all accounts, a guinea worm. Absolutely. So it's been with us for a while. For a long time, but it'll soon be gone. Well, so if there's ever a new New Testament, they'll mention you and say, he got rid of this. JC saved the day. The new New Testament with the new, new JC. That's exactly right. So you have cultural, traditional practices. Sure. And without referencing whether they work or not. But with this time, this one year time delay, one could invoke practically anything they happen to do at the time as a possible cure. Absolutely. And there were communities that were really upset about putting larvicides, something that will kill those water fleas because this is a place that has been life-giving to their families and they don't want anybody to mess with it. So what do you do about that? Getting a jar of water and filtering it and concentrating all those little fleas and showing someone in the light with a magnifying glass, all the stuff that's living in the water. In the water, after you've filtered it, convinces them that maybe they don't want to drink this. That would do it for me. And that's, got to tell you. But all that is is education and finding the right way to convey information. Humanity is not refractory to education and information. I disagree with you there, Mark. I'm sorry, I live in America. And we live in, Mark. We hate education. I mean, seriously, look at what happens when you talk about vaccines. And you give people the science and they say, no, no, no, you're just saying that because you're like part of the conspiracy. For example, I got to agree with Chuck on this. You're saying humans are fundamentally not refractory. Refractory to education. Sorry, my vocabulary is not there. So fine, but you look around and you see people in denial of the role of vaccines. Yes. You see measles outbreak in Disneyland. Agreed. So what are you saying? Well, I think the fault is that a couple of scientists incorrectly educated people about something that wasn't true. It's not that people are refractory to education. They're hungry for it. I got you. So it's one of our own. Of course. Et tu, Brute? But you know, I think the other thing is, going back to the getting one, when you talked about the demonstrable properties of being able to show people, I think that has a lot to do with it. That's potent. Because people are afraid of science. I don't know why, but they're just afraid of science. And if you can show them, like, hey, man, science is your friend. It's OK. I think they'll be more inclined to accept it. A lot of people were afraid of polio when it was killing their family members. Nobody's afraid of it anymore. Because of a vaccine. Right. Yeah. Exactly. Yeah. You know, I asked President Carter which nasty parasites or diseases he's targeting next. Coming up on StarTalk. Welcome back to StarTalk. I'm your host, Neil deGrasse Tyson. Chuck, Mark, we're trying to eradicate the guinea worm. Sure. My interview with President Carter took me to new places, and you've been helping me understand this problem, so thanks, thanks for that. Let me ask you, though, if the Carter Center manages to completely eradicate the guinea worm, a parasite that affects only human beings, it will go extinct, is that correct? That is correct. Now, you study parasites. You love use some parasites. Does this upset you? Not in the slightest. First of all, I think it- I don't know why I didn't expect you to say that. I thought you'd get all sentimental about it, right? I'm very sentimental about parasites, but I'm sentimental about my 11-year-old daughter, and I know that everyone who lives out there with an 11-year-old daughter or an eight-year-old daughter is sentimental about those people, too. I think that if there's a parasite that goes extinct, if we go extinct, then we don't have a moral responsibility to save it in the sense that for the guinea worm to not go extinct would require that we assign someone's child to carry it. Is that going to be your child? Is it going to be yours? Is it going to be mine? And are we going to do that out of some weird sense of ecological guilt? Are there colleagues of yours who think differently? Can you keep it alive? Can you put it in some cadaver leg or something just to keep it alive just because you find them amusing? No, although that's actually been done with smallpox, unfortunately. It's still around. People could still get infected. Guinea worm is an animal. Once you freeze an animal, for example, it's dead. It's not coming back. Do I have colleagues who disagree with me on this? None that I know of. And if they did, they wouldn't be my colleagues anymore. And if they did, just give them, let them be the hosts of the Guinea worm. You love it so much, why don't you marry it? But I would even be opposed to that because it maintains the possibility that you could have an outbreak in other people who didn't ask for it. And this is really where we get to even on measles. So I had to ask President Carter once the Guinea worm is eradicated because we're down 126 cases. So we're counting down to minutes on that. Which is huge. It's huge, down from millions. Three and a half million at least in 1986. Right, okay, so when he first took on this challenge. So I had to ask him, what's next? Let's find out what he told me. We have other diseases on our horizon. One would be Onchocerciasis or Rubell blindness. And another one might in the future be trachoma. That also causes blindness. And so we deal with matters of this kind. Malaria is another one that's not so neglected as others. With a huge fatality, I mean world fatality from malaria. Yeah, that's true. And so the Cortisone is constantly on the cutting edge of assessing which can diseases can be eliminated from a particular region. For instance, we're now just about eliminated all the rubber blindness or oncosarcasis in this hemisphere. We only have a tiny little tribe of people in the border between Venezuela and Brazil that still has rubber blindness. For six countries in Latin America, it's just about gone. So it'll soon be gone from this hemisphere. And we're working on that in Africa as well. So rubber blindness is on the target. So Mark, what is river blindness? River blindness is caused by the larval stages of another nematode, instead of it being in like a water flea, like any worm. A nematode is your word for what we call worms. It's a worm, sure. Why don't you all just say worms then? Why do you have to make a three-letter, a three-syllable... Well, because leeches are worms too, and they're not the same. I could go on for an hour about worms. Okay, okay. I will stick with nematode. Let the man have his nematode. I didn't mean to get in his nematode. Okay, go. River blindness is a condition that is caused by a worm called onchocercoboldulus, which we call onco because that's easier. Right. But the larval stages will run around in your body underneath the skin. They get in by the bite of a black fly. That's why it's called river blindness because... Of course, it's got to be a black fly. I keep telling you, Chuck, it's not... It's okay. I'm just saying. They get in by the bite of a fly in the family simulidae that happened to be very dark in color. But the larvae run around... It's a multiracial fly. River fly. We should call them river flies. Because they actually lay their eggs in rivers, very fast-flowing water. That's why it's called river blindness. But the larvae get around... Then they start getting across the eyes and they scar the cornea. And that causes blindness. Now, there are whole communities in Africa that for hundreds of years, if not thousands of years, the young lead the blind. Because when you get to 20 years old, you're blind. That's just the way it goes. It's awful. So what parasites do you want to see eradicated next? Does your list agree with the presidents? Yeah, my list actually agrees very clearly with the presidents and the World Health Organization and the Center for Disease Control. And there are a few things that really make a disease eradicate Ebola. I wish Ebola was, but it's not, because there are reservoir hosts like bats. The things that really just involve humans are things that we can get in front of, where we've got the technology. Maybe it's a... Good reason to prioritize those. Absolutely. We could get these things done in 15 to 20 years. So maybe we need more science fiction movies that show parasites. Because Alien had parasites, Amethyst. I got my list there. Star Trek 2? No, no, Star Trek. Yes, that's the earwig, man. The earwig? Oh, that was nasty. Rathacon. Rathacon, they put him on his knees, and he's just like, oh. I have recovered from that scene. I'm still freaking out about it. So, I mean, in the real world, you know, my friend Bill Nye, the science guy, he's going to explain why scientific advances you probably take for granted may be the only reason why you're alive today. Unstart. We are back on StarTalk, talking about diseases. Yes. And parasites. Yes. And stuff. You know, in this segment, we occasionally like to feature a little contribution from a good friend of mine, Bill Nye, the science guy. He recently moved to New York City, and so anytime we get him to contribute to StarTalk, we have to chase him down and catch up with him wherever we happen to find him. Well, we've been talking about parasites, and he has something to say about how science can help keep us alive from things that would have surely killed us in a time gone by. Greetings, sir. May I have a hot dog, a mustard and relish? Thanks. If you're a big living thing, like a human, you might think your enemies are lions and tigers and bears. Oh my, but oh no. No, it's tiny things like germs and parasites. They've wiped out whole societies and civilizations with things like the bubonic plague, Ebola and the flu. And who knows what else is out there in the bush or elsewhere just waiting to come and get us. You need a microscope and special skills even to see it in the first place. That's why so many people around the world have trouble accepting how dangerous they can be. Many germs and parasites enter our bodies through the water we drink. So by understanding the science of disease, we've designed filters that are so fine, they block out the germs and parasites and don't let them enter our bodies in the first place. We've been able to preserve the lives of millions of people around the world, raising their quality of life and making them more productive so that people everywhere enjoy longer, healthier lives. It's wonderful. Oh, man. Oh, it was wonderful. Wow. Bill Nye died 12 hours later from eating that hot dog. Yeah, I was going to say, half the stuff he talked about was on that hot dog. No, Bill Nye said it all. I mean, the real enemy is microscopic. And you said earlier in this show, that we're not just humans living apart from the rest of the bacterial kingdom, that they are within us. Absolutely. Living and working. Where a human or where the human species starts and stops is actually very fuzzy, and the fuzziness comes from our... Wait, wait, wait, that sentence is freaking me out. Say it again, but don't freak me out. What do you mean? The definition of a human is fuzzy. What does that even mean? Well, the definition of a human is pretty clear. Your skin stops here, but then there's the bacteria on it, and then maybe the virus on the bacteria, so maybe it's not right there. But that goes for the species too. Well, the boundary. Yeah, so where does the species start and stop? And then you go interior. So where do I end my bacteria beginning? But then there are things that move between you and other human beings that can only move between you and other human beings. Yes, and I had that checked out. And apparently... Went to the clinic. All I'm saying is they gave me some pills and everything's fine now. I think fundamentally... You know, it's... As a parasitologist, I look at the world through different glasses, and I don't see people or species as these separate entities. They're all connected through things they eat and where they crap and who eats whose crap. But there's this intricate, deep, web-like connection of all of life, and parasites are just a great manifestation of that. How many species of living organisms exist within us? In any given moment, approximately? 200,000? Wow! Well, when you call, I mean, the viruses and the bacteria and the... So we are vessels for the lives of 200,000 different species of microorganisms. I hate to say something as trade as we're all connected, but we're evolved in concert with the microbiota, the parasites. No creature on earth lives or dies in vain. Exactly. Guys, we got to wrap this up. This has been fun. I feel like enlightened. Mark, it's great to have you back again. Thank you for letting me be here. It has been an honor to work with President Carter on this exhibition, and I'm really happy that you're really talking about it here on the program. Yeah, we're talking about it. And Chuck, thanks as always for being on StarTalk. Guys, we're out of here. This has been StarTalk from the whole of the universe at the American Museum of Natural History. I've been your host, Neil deGrasse Tyson, your personal astrophysicist, and as always, I bid you all to keep looking out.