How do you get entangled particles? Neil deGrasse Tyson and comic co-host Chuck Nice unpack the experimental side of entanglement, superposition, and the quantum underpinnings of our universe with experimental physicist, Sean Hodgman.

What’s the real difference between dreaming and waking consciousness? Neil deGrasse Tyson and co-hosts Chuck Nice and Gary O’Reilly sit down with sleep expert Matt Walker to answer fan questions about the most mysterious thing humans do every single night: sleeping & dreaming.

What type of planets orbit black holes? Neil deGrasse Tyson and comic co-host Negin Farsad sit down with Mordecai-Mark Mac Low to crack open the mysteries of galaxy collisions, dark matter, and the massive planetary systems around black holes.

Did evolution never give us the ability to see reality as it actually is? Neil deGrasse Tyson and co-hosts Chuck Nice and Gary O’Reilly sit down with cognitive scientist Donald Hoffman to explore what neuroscience, evolutionary game theory, and consciousness suggest about the nature of reality itself.

What would happen in a world with too much oxygen? Neil deGrasse Tyson and Chuck Nice break down how rocks actually float, warm blankets, and why oxygen isn’t actually flammable.

Have aliens already secretly visited us? Neil deGrasse Tyson sits down with Steven Spielberg and screenwriter David Koepp to discuss their new film Disclosure Day, alien contact, and why Spielberg believes there’s more out there than meets the eye.

Is the fear of heights innate or learned? Neil deGrasse Tyson, Chuck Nice, and Gary O’Reilly explore taking risks, the neuroscience of fear, and how to overcome it with freestyle rock climber and subject of the film Free Solo, Alex Honnold, and neuroscientist Heather Berlin.

Did the Milky Way used to be a quasar? On this episode, Neil deGrasse Tyson and comic co-host Chuck Nice explore quasars, the high energy universe, and the movie we’re making of the night’s sky with astrophysicist & host of PBS Space Time, Matt O’Dowd.

Are all galaxies redshifting away? Neil deGrasse Tyson and comedian Negin Farsad tackle a grab bag of fan questions covering cosmic infrastructure, redshift, werewolves, gravitational waves, and the nature of time itself.

Can we put the data centers in space? Neil deGrasse Tyson and co-hosts Chuck Nice and Gary O’Reilly map out the future of human habitation, research, and industry in low Earth orbit with Ariel Ekblaw, founder and CEO of the Aurelia Institute.
